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RESEARCH

Vitamin D3 and Health

A closer look at what Vitamin D does in the body — and what supplementation research does not show.

Vitamin D3 and Health
Study type
NIH nutritional evidence + large randomized clinical trial
Published
2019
Dose studied
2,000 IU/day
Population
18,353 adults aged 50+
Key outcome
Vitamin D has established nutritional roles, but long-term supplementation did not meaningfully improve mood scores in this large trial.

About the study

Vitamin D is an essential nutrient involved in calcium absorption and normal bone, muscle, nerve, and immune function.

Those nutritional roles are well established.

That does not mean Vitamin D should automatically be presented as a “calming” ingredient.

One of the strongest reasons to include Vitamin D honestly on this page is to show where the evidence doesn't support a popular marketing narrative.

Read the original study

Key takeaway

Vitamin D3 has important nutritional functions, but this large randomized trial does not support using vitamin D supplementation as a general mood-improvement claim.

What the research found

The VITAL-DEP trial included 18,353 adults aged 50 or older.
Participants were randomized to receive 2,000 IU/day of vitamin D3 or placebo.
After a median follow-up of 5.3 years, vitamin D3 supplementation did not produce a meaningful improvement in mood scores.

Important context

Vitamin D's role in the formula is primarily nutritional, not a promise of a calming or mood-altering effect.
That distinction matters.
We would rather tell you what Vitamin D actually does than force every ingredient into the same “calm” story.

Study details

What this means for SUPRACALM: Vitamin D3 has established nutritional functions, but we do not use those functions as evidence that SUPRACALM produces a calming or mood effect. That's intentional. A science page should also tell you where the evidence stops. Science-backed ingredients

Science-backed
ingredients for
a calmer you.

Curious how it fits your evening?

SUPRACALM brings these four researched ingredients together in one simple, great-tasting daily drink.

Shop SUPRACALM
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